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Certes, il existe une relative proportionnalit entre lintensit de consommation et le risque cardio-vasculaire et celui de cancer, mais ce risque est dj significativement prsent et relativement lev pour une consommation de quelques cigarettes [2,3]

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More useful systems may include synovium-cartilage co-culture, tissue explants, and whole-joint or organoid-like models, because they can better reflect immune-stromal interactions than single-cell systems