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The insula, a functionally heterogeneous region, is involved with monitoring the physiological state of the body, appears causally related to the initiation, maintenance, and adjustment of attentional control, and likely plays a role in maladaptive decision-making among drug addicts [7982]

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Learning the hard way Allan Brandt, history of science scholar and Cigarette Century author, says opioid negotiators should heed lessons from tobacco settlement As state and local officials weigh proposed multibillion-dollar settlements to resolve cases against Purdue Pharma, Johnson & Johnson, and other drug companies in the U.S