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Analyses will be conducted by the Penn State TCORS Biostatistics Core using statistical software SAS version 9.4 or higher (SAS Institute, Cary, NC, USA) and the R programming language version 3.3.2 or higher (R Foundation)

Similar content being viewed by others Introduction Emphysema is a type of chronic obstructive pulmonary disease (COPD) and it is pathologically defined as an abnormal dilation of air spaces distal to the terminal bronchiole, accompanied by the destruction of alveolar walls 1

Some people are not aware of brushing at night, some forget, some remember to brush at night, but are lazy, and some find it difficult to make a commitment to not eat anything after that