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While nicotine can have mild cardiovascular effects, such as increasing heart rate, the major causes of smoking-related illness come from toxic smoke exposure rather than nicotine itself

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Philip Morris made cigarettes at Auschwitz in the 1990s A study of tobacco industry documents reveals that the maker of Marlboro cigarettes manufactured its deadly products inside the former Nazi death camp

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The first commercially successful vape was invented by Chinese pharmacist Hon Lik 1 in 2003