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Therefore, its easy for people to be discouraged from consuming it since it has already been linked to many health risks like cancer and oral health issues
Despite the obvious biologic plausibility, the lack of consistent epidemiological evidence might be due to methodological issues including lack of cohort follow-up time into older adulthood (when lung cancer usually becomes clinically manifest), small sample sizes, selection and recall biases, and lack of adjustment for tobacco use in the statistical modeling
Since the testing system detects the nicotine metabolite, the window of detection in oral fluid starts almost immediately after tobacco use and can last up to about three days
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