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In September 2021, Pfizer voluntarily pulled branded Chantix from the market due to contamination with nitrosamines, a carcinogen that has tainted the production of numerous medications in recent years, including ranitidine, nizatidine, and metformin

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Long-Term Use Comes with Hidden Costs Nicotine replacement therapies (NRTs) like gums, patches and lozenges were designed for short-term use typically 8 to 12 weeks

Scans were also taken of the brains of more than 5,000 of the children between the ages of 9 and 13, looking at brain volume and the "microstructures" of the brain