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This interaction between asthma and cigarettes smoking creates a vicious cycle: the more inflammation increases, the more reactive the airways become, and the more lung function gradually deteriorates

George V was concerned not only that his eldest son David would sabotage his own reign when he inherited, but also that next-in-line Bertie, himself frail and suffering from lung congestion, would not last the course either

When mouse ex-smokers (that normally feature low ACG levels) were given an ACG supplement, they failed to gain weight upon smoking cessation, suggesting that ACG acted in this context as a weight-reducing metabolite

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