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However, as cells age, the chance of accumulating harmful mutations increases and cancer cells can start to grow
When absorbed through the skin via a patch, or through the mouth and stomach when chewing nicotine gum, nicotine is absorbed more slowly and therefore takes longer to reach the brain
Specific binding volume of distribution (V S /f P ), a measure proportional to 4 2 * nAChR density, was determined for regions known to have nAChR upregulation with smoking (prefrontal cortex, brainstem, and cerebellum)
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