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Front Pharmacol 15:1392027 McEwan M, Azzopardi D, Gale N et al (2022) A randomised study to investigate the nicotine pharmacokinetics of oral nicotine pouches and a combustible cigarette

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And if you remove the ones that have been supported by the makers of the nicotine-delivery devices, theres really not adequate evidence that e-cigarettes are beneficial. For now, the FDA has funded 48 research projects to find out more

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