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Each includes the Nicotiana tabacum plant, whether in its natural state or substitutes, and is used for smoking, chewing, or sniffing
The use of areca nut (30%) and betel quid with tobacco (28%) were the most significant contributors to oral cancer cases among women, followed by the consumption of gutka and khaini, each accounting for 21% of cases
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Most users of chewing tobacco in the USA are men, though some American Indian and Alaskan Native communities typically have a relatively high prevalence of using these products
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