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The authors of this paper are skeptical, noting that such stigmatization could instead lead to feelings of powerlessness

She went the extra mile making sure I's were dotted and T's were crossed

Alternatively, statistical control of baseline smoking can also address this issue to some extent

Figure 2 3.3 Enhanced 5-HT 1A R signaling persists after adolescent pretreatment with nicotine or fluoxetine Adolescent treatment with fluoxetine or nicotine induces persistent alteration in 5-HT 1A receptor signaling, even after drug pretreatment has ended