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Without measures of these two things, a study wont hold up in the lab

While in this short-term study, there was no association between exclusive e-cigarette use and cardiovascular events, there was an association with incident COPD and possibly hypertension that will need to be closely watched over longer-term follow-up. Blaha says the new study suggests that e-cigarettes have definite potential health risks, although the risks may be less than what is seen for traditional combustible cigarette smoking alone

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Over 95% of PLCH patients are smokers and it is estimated that the disease affects approximately 34% of smokers