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Smoking causes considerable harm (see: The importance of overcoming a deadly habit: the harms caused by smoking and progress towards smokefree goals), but evidence suggests that cessation has both immediate and long-term benefits on a persons health and quality of life (Figure 1)

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The present study, as part of the Global Burden of Diseases, Risk Factors, and Injuries Study (GBD) 2020, re-estimated the continuous doseresponse relationships (the mean risk functions and associated uncertainty estimates) between current smoking and 36 health outcomes (Supplementary Table 1) by identifying input studies using a systematic review approach and employing a meta-analytic method 28

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