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These effects hold true for all forms of tobacco use, whether smoking cigarettes or using smokeless tobacco products, including chewing tobacco and snuff

Additionally, the increased risk of lung cancer is a grave consequence of smoking, as carcinogens present in tobacco smoke can initiate malignant transformations in lung tissues

that is, cigarettes allow smokers to adjust their puffing patterns to regulate their intake of nicotine, regardless of how the cigarette might perform under the standard testing conditions that drove the labeling and advertising of the products

While the overall global market share of MNCCs decreased slightly from 2010 to 2020, trends were relatively stable across all WHO regions and country income groups