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and the percentage of 11-17 year olds who have used an e-cigarette in the past month has doubled in Italy since 2014 and increased significantly in Latvia and Romania

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Toxic Chemical Accumulation Tobacco smoke contains over 7,000 chemical compounds, many of which accumulate in hair follicles and surrounding tissues

Thus, we proposed that nicotine directly affects the migration of VSMCs from the tunica media to atheromatous plaques in the vascular intima by inducing the transformation from a contractile-type to a synthetic-like type, which occurs before the development of atheromatous plaques

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