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Pyrilamine is reported to be taken up from carrier-mediated transport with the involvement of H+/organic cation antiporter that drives H+ outward for its uptake, similar to that of nicotine, suggesting both molecules share a similar transport system for its uptake into the brain endothelial cells (Okura et al., 2008)

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Taken together, SNX1 and SNX2, as well as RAB5 (ARA7), RAB7 (RABG3f), and the retromer complex are essential for proper VSR targeting, which play a critical role in seed development and germination in plants

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